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Signal Transduction - Bastien-D Gomperts

PRIX: GRATUIT
FORMAT: PDF EPUB MOBI
DATE DE SORTIE: 01/01/2002
TAILLE DU FICHIER: 4,30
ISBN: 0-12-289631-9
LANGUE: FRANÇAIS
AUTEUR: Bastien-D Gomperts

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Description:

Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how tells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevante to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signaling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work. Throughout, the authors take the opportunity to confront controversies, to discuss ambiguities and to challenge dogma, while margin notes provide entertaining asides.

...x secondaires, internes à la cellule (« signalling ») ou externes (ex: action sur d'autres types cellulaires via des interleukines), et des processus cellulaires internes (métabolisme ... Signal Transduction de Bastien-D Gomperts - Livre - Decitre ... ... Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. Signal Transduction Definition. Signal transduction is the proce ... signal transduction - Traduction française - Linguee ... .Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. Signal Transduction Definition. Signal transduction is the process of transferring a signal throughout an organism, especially across or through a cell.Signal transduction relies on proteins known as receptors, which wait for a chemical, physical, or electrical signal.Chemical signals are called ligands, and can be produced by organisms to control their body or received from the environment. Before Pawson's pioneering work on signal transduction, it was generally not accepted that proteins could interact in such specific ways. innovationcanada.ca. innova...